In Vivo Assessment of Pediatric Fracture Healing

Longitudinal imaging of bone repair during pubertal growth.

Our lab is investigating how bone repairs itself during pubertal growth following fracture and why healing differs between individuals. Using longitudinal high-resolution imaging (HR-pQCT) of wrist fractures, we examine the biological and mechanical processes that drive bone regeneration, from early callus formation to the restoration of normal bone structure and strength.

A major focus is understanding how factors such as obesity, growth, and muscle strength influence fracture healing and recovery.

Researcher sharing a model of a leg cast with a child

Project Details

Funding: SickKids ECR Operating Grant.

Related selected publication

Structural alterations during fracture healing lead to void spaces developing in surrounding bone microarchitecture.
DE Whittier, M Walle, PR Atkins, CJ Collins, MA Zumstein, P Christen, K Lippuner, R Müller
Journal of Bone and Mineral Research  ·  03 Jun 2025  ·  pubmed:40118761

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