Clinical Research
Our clinical research develops multimodal imaging methods to study bone growth, development, repair, and joint health in pediatric populations affected by chronic and complex diseases.
Clinical Imaging Research
We develop and apply advanced imaging methods to study bone health in children and adolescents affected by chronic disease, musculoskeletal disorders, and injury. By combining longitudinal cohort studies with multimodal imaging, we investigate how bone microarchitecture changes throughout growth, treatment, and recovery.
Areas of interest
- Longitudinal pediatric cohort studies
- Bone microarchitecture using HR-pQCT
- Clinical CT, MRI, radiography, and ultrasound
- Computational image analysis and AI
- Quantitative imaging biomarkers
Current Projects
This SickKids ECR Operating Grant-funded project investigates how bone repairs itself during pubertal growth following fracture and why healing differs between individuals.
This project uses advanced musculoskeletal imaging and computational modelling to study why children with obesity can have elevated fracture risk despite higher bone mineral density.
This project uses multimodal imaging to study bone microarchitecture and erosions in juvenile idiopathic arthritis, with the goal of improving diagnosis, monitoring, and treatment.
Methods
This stream combines high-resolution imaging, clinical cohorts, computational modelling, and measures of growth, muscle, and function to better understand pediatric bone health.